| Dataset | RNR_GSEA_DESEQ2_FC |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS |
| Enrichment Score (ES) | 0.23988695 |
| Normalized Enrichment Score (NES) | 3.1990926 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CBLC | 117 | 1.995 | 0.0012 | Yes | ||
| 2 | FBXW7 | 1272 | 0.416 | -0.0537 | Yes | ||
| 3 | KLHL13 | 1359 | 0.385 | -0.0508 | Yes | ||
| 4 | UBE4A | 2173 | 0.242 | -0.0872 | Yes | ||
| 5 | TRAF6 | 2441 | 0.214 | -0.0941 | Yes | ||
| 6 | SOCS1 | 2523 | 0.209 | -0.0910 | Yes | ||
| 7 | PIAS1 | 2572 | 0.204 | -0.0861 | Yes | ||
| 8 | CDC20 | 2825 | 0.183 | -0.0922 | Yes | ||
| 9 | BRCA1 | 2859 | 0.182 | -0.0865 | Yes | ||
| 10 | FBXW11 | 2922 | 0.177 | -0.0823 | Yes | ||
| 11 | NEDD4 | 3165 | 0.162 | -0.0879 | Yes | ||
| 12 | UBA6 | 3212 | 0.159 | -0.0828 | Yes | ||
| 13 | UBE2H | 3382 | 0.152 | -0.0844 | Yes | ||
| 14 | UBOX5 | 3684 | 0.136 | -0.0932 | Yes | ||
| 15 | KLHL9 | 3728 | 0.134 | -0.0880 | Yes | ||
| 16 | CBL | 3775 | 0.132 | -0.0830 | Yes | ||
| 17 | HUWE1 | 3780 | 0.132 | -0.0757 | Yes | ||
| 18 | BIRC6 | 3807 | 0.130 | -0.0695 | Yes | ||
| 19 | PARK2 | 4108 | 0.118 | -0.0782 | Yes | ||
| 20 | UBR5 | 4135 | 0.117 | -0.0721 | Yes | ||
| 21 | BTRC | 4138 | 0.117 | -0.0647 | Yes | ||
| 22 | XIAP | 4561 | 0.102 | -0.0800 | Yes | ||
| 23 | DET1 | 4611 | 0.101 | -0.0751 | Yes | ||
| 24 | HERC2 | 4738 | 0.096 | -0.0744 | Yes | ||
| 25 | MAP3K1 | 4779 | 0.095 | -0.0691 | Yes | ||
| 26 | HERC1 | 4800 | 0.094 | -0.0626 | Yes | ||
| 27 | UBE2Q2 | 4977 | 0.089 | -0.0646 | Yes | ||
| 28 | SMURF2 | 4989 | 0.089 | -0.0577 | Yes | ||
| 29 | PIAS2 | 5041 | 0.088 | -0.0530 | Yes | ||
| 30 | SMURF1 | 5151 | 0.085 | -0.0513 | Yes | ||
| 31 | UBA1 | 5194 | 0.083 | -0.0461 | Yes | ||
| 32 | ITCH | 5215 | 0.083 | -0.0396 | Yes | ||
| 33 | UBE2W | 5264 | 0.081 | -0.0347 | Yes | ||
| 34 | UBA3 | 5298 | 0.081 | -0.0290 | Yes | ||
| 35 | MID1 | 5329 | 0.080 | -0.0231 | Yes | ||
| 36 | HERC4 | 5338 | 0.079 | -0.0160 | Yes | ||
| 37 | ANAPC1 | 5365 | 0.079 | -0.0099 | Yes | ||
| 38 | RHOBTB2 | 5412 | 0.078 | -0.0049 | Yes | ||
| 39 | UBE4B | 5441 | 0.077 | 0.0011 | Yes | ||
| 40 | TRIP12 | 5493 | 0.075 | 0.0059 | Yes | ||
| 41 | UBE3A | 5522 | 0.074 | 0.0119 | Yes | ||
| 42 | UBE2QL1 | 5575 | 0.073 | 0.0166 | Yes | ||
| 43 | FBXW8 | 5698 | 0.070 | 0.0175 | Yes | ||
| 44 | DDB1 | 5865 | 0.066 | 0.0161 | Yes | ||
| 45 | TRIM32 | 5893 | 0.065 | 0.0221 | Yes | ||
| 46 | FBXO4 | 5906 | 0.064 | 0.0290 | Yes | ||
| 47 | SKP1 | 5977 | 0.062 | 0.0328 | Yes | ||
| 48 | HERC3 | 6172 | 0.058 | 0.0298 | Yes | ||
| 49 | CUL4B | 6180 | 0.058 | 0.0369 | Yes | ||
| 50 | CUL1 | 6347 | 0.054 | 0.0355 | Yes | ||
| 51 | UBA2 | 6375 | 0.053 | 0.0415 | Yes | ||
| 52 | CUL5 | 6418 | 0.052 | 0.0468 | Yes | ||
| 53 | TCEB2 | 6466 | 0.051 | 0.0518 | Yes | ||
| 54 | WWP1 | 6741 | 0.045 | 0.0445 | Yes | ||
| 55 | NEDD4L | 6909 | 0.042 | 0.0430 | Yes | ||
| 56 | NHLRC1 | 6951 | 0.041 | 0.0483 | Yes | ||
| 57 | CUL4A | 6965 | 0.040 | 0.0551 | Yes | ||
| 58 | CBLB | 7063 | 0.038 | 0.0573 | Yes | ||
| 59 | UBE2Z | 7101 | 0.037 | 0.0629 | Yes | ||
| 60 | UBE2G2 | 7123 | 0.037 | 0.0692 | Yes | ||
| 61 | ANAPC13 | 7232 | 0.035 | 0.0709 | Yes | ||
| 62 | UBE2G1 | 7327 | 0.032 | 0.0734 | Yes | ||
| 63 | FZR1 | 7478 | 0.029 | 0.0728 | Yes | ||
| 64 | UBE2S | 7497 | 0.029 | 0.0793 | Yes | ||
| 65 | UBE3B | 7632 | 0.026 | 0.0796 | Yes | ||
| 66 | CUL3 | 7686 | 0.025 | 0.0843 | Yes | ||
| 67 | ERCC8 | 7917 | 0.021 | 0.0793 | Yes | ||
| 68 | UBE2A | 8073 | 0.018 | 0.0785 | Yes | ||
| 69 | ANAPC5 | 8246 | 0.014 | 0.0767 | Yes | ||
| 70 | SIAH1 | 8256 | 0.014 | 0.0837 | Yes | ||
| 71 | VHL | 8461 | 0.010 | 0.0802 | Yes | ||
| 72 | UBE2E2 | 8481 | 0.010 | 0.0867 | Yes | ||
| 73 | UBE2D3 | 8727 | 0.004 | 0.0810 | Yes | ||
| 74 | UBE2L6 | 8732 | 0.004 | 0.0883 | Yes | ||
| 75 | RCHY1 | 8761 | 0.004 | 0.0943 | Yes | ||
| 76 | ANAPC10 | 8773 | 0.004 | 0.1012 | Yes | ||
| 77 | UBE3C | 8838 | 0.002 | 0.1053 | Yes | ||
| 78 | SKP2 | 8899 | 0.001 | 0.1095 | Yes | ||
| 79 | SAE1 | 8905 | 0.001 | 0.1168 | Yes | ||
| 80 | UBE2O | 9160 | -0.004 | 0.1106 | Yes | ||
| 81 | UBE2I | 9171 | -0.005 | 0.1176 | Yes | ||
| 82 | CUL7 | 9185 | -0.005 | 0.1244 | Yes | ||
| 83 | PPIL2 | 9356 | -0.008 | 0.1227 | Yes | ||
| 84 | TCEB1 | 9412 | -0.009 | 0.1273 | Yes | ||
| 85 | UBE2M | 9516 | -0.011 | 0.1292 | Yes | ||
| 86 | CUL2 | 9562 | -0.012 | 0.1343 | Yes | ||
| 87 | PML | 9601 | -0.013 | 0.1398 | Yes | ||
| 88 | ANAPC4 | 9604 | -0.013 | 0.1472 | Yes | ||
| 89 | CDC16 | 9651 | -0.014 | 0.1522 | Yes | ||
| 90 | PIAS3 | 9759 | -0.016 | 0.1539 | Yes | ||
| 91 | TRIM37 | 9870 | -0.018 | 0.1555 | Yes | ||
| 92 | ANAPC2 | 9913 | -0.019 | 0.1608 | Yes | ||
| 93 | UBE2L3 | 9967 | -0.020 | 0.1654 | Yes | ||
| 94 | STUB1 | 10076 | -0.022 | 0.1671 | Yes | ||
| 95 | UBE2R2 | 10146 | -0.023 | 0.1709 | Yes | ||
| 96 | BIRC2 | 10185 | -0.024 | 0.1763 | Yes | ||
| 97 | RBX1 | 10323 | -0.026 | 0.1765 | Yes | ||
| 98 | UBE2K | 10366 | -0.027 | 0.1817 | Yes | ||
| 99 | SYVN1 | 10390 | -0.028 | 0.1880 | Yes | ||
| 100 | UBA7 | 10407 | -0.028 | 0.1946 | Yes | ||
| 101 | ANAPC11 | 10787 | -0.036 | 0.1817 | Yes | ||
| 102 | UBE2E1 | 10932 | -0.040 | 0.1814 | Yes | ||
| 103 | UBE2B | 10935 | -0.040 | 0.1888 | Yes | ||
| 104 | CDC27 | 10947 | -0.040 | 0.1957 | Yes | ||
| 105 | WWP2 | 11037 | -0.042 | 0.1984 | Yes | ||
| 106 | UBE2D2 | 11080 | -0.044 | 0.2037 | Yes | ||
| 107 | BIRC3 | 11161 | -0.045 | 0.2069 | Yes | ||
| 108 | MDM2 | 11200 | -0.046 | 0.2123 | Yes | ||
| 109 | UBE2N | 11206 | -0.047 | 0.2196 | Yes | ||
| 110 | FANCL | 11266 | -0.048 | 0.2239 | Yes | ||
| 111 | UBE2D1 | 11279 | -0.048 | 0.2308 | Yes | ||
| 112 | PRPF19 | 11386 | -0.051 | 0.2326 | Yes | ||
| 113 | PIAS4 | 11499 | -0.053 | 0.2340 | Yes | ||
| 114 | UBE2E3 | 11531 | -0.054 | 0.2399 | Yes | ||
| 115 | KEAP1 | 12058 | -0.066 | 0.2190 | No | ||
| 116 | CDC34 | 12218 | -0.070 | 0.2179 | No | ||
| 117 | RFWD2 | 12245 | -0.071 | 0.2240 | No | ||
| 118 | CDC26 | 12334 | -0.073 | 0.2268 | No | ||
| 119 | UBE2J1 | 12356 | -0.073 | 0.2332 | No | ||
| 120 | UBE2Q1 | 12682 | -0.083 | 0.2231 | No | ||
| 121 | RNF7 | 12703 | -0.083 | 0.2295 | No | ||
| 122 | CDC23 | 12726 | -0.084 | 0.2359 | No | ||
| 123 | ANAPC7 | 12933 | -0.090 | 0.2323 | No | ||
| 124 | DDB2 | 13427 | -0.106 | 0.2131 | No | ||
| 125 | UBE2D4 | 13459 | -0.107 | 0.2190 | No | ||
| 126 | UBE2J2 | 13626 | -0.112 | 0.2175 | No | ||
| 127 | UBE2F | 14234 | -0.140 | 0.1922 | No | ||
| 128 | UBE2C | 14685 | -0.163 | 0.1754 | No | ||
| 129 | MGRN1 | 15801 | -0.263 | 0.1226 | No | ||
| 130 | AIRE | 17053 | -0.519 | 0.0625 | No | ||
| 131 | SOCS3 | 17139 | -0.551 | 0.0655 | No | ||
| 132 | FBXO2 | 17178 | -0.570 | 0.0709 | No | ||
| 133 | UBE2U | 17491 | -0.731 | 0.0616 | No |
